CBD Oil Manufacturers

CBDISTILLERY

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This article provides an overview of CBD oil suppliers in both the United States and global markets. Deciding which CBD manufacturers to partner with is one of the most significant decisions that business owners of CBD companies will ever make. From the top-down, each decision that CBD oil manufacturers and suppliers make will ultimately reflect on the business. After all, you’re selling these products to your custome 10 Best CBD Companies to Buy From in 2022: Honest Reviews & Guide To find the best CBD oil companies on the market, we devised a set of criteria that we applied to each brand that we considered.

Top Suppliers of Cannabidiol (CBD) Oil

Cannabidiol (CBD) oil is a chemical compound found in the Cannabis sativa plant. It is only one of hundreds of cannabinoids, but makes up for 40% of the plant’s extract, coming from the flowers and leaves. As CBD suppliers can tell you, CBD is becoming one of the highest growing homeopathic medicines and is well-known for its pain relief properties. Cannabidiol is non-psychoactive and CBD oils are made from extracting cannabidiol from the cannabis plant and then adding an emulsifier, commonly hemp or coconut.

CBD oil is primarily used to relieve pain, reduce anxiety and depression, and is even used to fight symptoms in illnesses such as cancer, multiple sclerosis, and epilepsy. The passing of the Farm Bill in 2018 has made it easier to sell CBD products in the United States, although it is still not sold everywhere. The CBD market is one of the fastest-growing markets today. In 2016, Forbes reported that the market is expected to manifest a 700% increase in four years, reaching $2.1 billion by 2020. In this guide, we’ll be going over the top cbd companies, both domestic and global, to help you source for what you need.

Please note: While cannabis, CBD, hemp, and other products have been undergoing a wave of legalization across the US, laws still vary from state to state. Since these products are so new to the market, regulation of them is still ongoing; even the FDA has only had time so far to approve prescription CBD products. Because of this, it’s important to find a reputable supplier. CBD buyers should look for:

  • Proof of testing from a lab with ISO 17025 standards
  • A certificate of analysis (also known as a COA) that shows the products have no pesticides, mold, or heavy metals, as well as a THC level of .3% or less.
  • an FDA warning letter or bad reviews for the supplier
  • Whether the supplier has made unrealistic or unsupported claims

If you’d like to learn more about the business side of things, including sourcing, regulations, and more, you can also check out our guide on how to start a cannabusiness.

Top Domestic CBD Oil Suppliers

Below in Table 1 is a list of the top U.S.-based suppliers of CBD oil distributors and manufacturers. These companies are mostly located in the West, where CBD and other hemp-based products are easier to sell. Estimated annual revenues are in millions of U.S. dollars.

Table 1 – Top U.S.-based Suppliers of CBD Oil

Company

Headquarters

Estimated Annual Revenue

Year Founded

Company Summaries

Medical Marijuana is credited with developing the first legal supply of CBD, and also being the first publicly-traded CBD company in the United States. Founded in 2009, Medical Marijuana has eight brands of CBD products and four different subsidiary companies. Their products include CBD oils, as well as hemp foods, clothing, and body care products.

CV Sciences was founded in 2010 and focuses on two major markets: pharmaceuticals and consumers. CV Sciences sells various botanical-based CBD products for consumers and can be founded in health food stores. Their current pharmaceutical pursuits include the development of a cannabidiol-based medicine pending FDA approval. CV Sciences acquired CanX in 2015 and is working on developing a nicotine and CBD gum to fight tobacco addiction.

Gaia Herbs has an extensive product line of natural remedies and supplements; included in this list is their hemp extract oils, sold in different sizes. Founded in 1987, Gaia Herbs has made a commitment to creating sustainable and clean products. They are a Certified B company, as a commitment to their environmental and social responsibilities. Gaia Herbs products are chemical fertilizer and pesticide-free and do not use GMO seeds.

Charlotte’s Web is a CBD supplier with a unique formula to other CBD products, with a high amount of cannabidiol and low THC (some products are even THC free). Charlotte’s Web is a family-owned company of seven brothers, originally founded in 2011. Their product line includes CBD oil, gummies, and capsules, as well as CBD products for dogs. Their CBD oils are also available in different flavors, such as mint chocolate, lemon, and orange blossom.

CBDistillery was founded in Denver Colorado in 2016 and makes a commitment to selling fairly-priced products. Their line includes CBD oils, capsules, isolate, and creams. Their CBD products are made from non-GMO industrial hemp with natural farming and contain no THC. Their products are also offered wholesale and are all tested by a third party.

Founded in 2014, NuLeaf Naturals offers natural, lab-tested, and organic CBD oils and extract products. Their CBD is whole-plant extract and made with organic and sustainable farming and a unique CO2 extraction system to retain the entire spectrum of cannabinoids. Their CBD oils are sold in different dosages, in wholesale options and retail locations across the United States.

Top Global (Non-U.S.-based) CBD Oil Suppliers

Below in Table 2 is a list of the top CBD oil manufacturers and distributors not based in the United States. CBD oil remains somewhat controversial in the United States due to its affiliation with other cannabidiol products, and so it is not sold all throughout the country. Other countries have different laws in regards to the manufacturing and selling of CBD oil. Estimated annual revenues are in millions of U.S. dollars.

CBD Manufacturers: 5 Reasons to Choose Joy

Deciding which CBD manufacturers to partner with is one of the most significant decisions that business owners of CBD companies will ever make. From the top-down, each decision that CBD oil manufacturers and suppliers make will ultimately reflect on the business. After all, you’re selling these products to your customers, and they’re trusting you with their health. You want to make sure that everything from the farm to the manufacturing facility remains current with licenses and certificates, and performs third-party lab testing. These are all steps we took when we started Joy Organics.

We were very meticulous about choosing our CBD oil suppliers. Our brand’s reputation depends on their compliance with federal law, use of organic practices, and transparency with seed-to-sale cycle tracking. We’ll discuss the characteristics of good CBD oil manufacturers, certificates of analysis (COAs) you should look for, and how Joy Organics can help your brand become one of the top CBD companies in the market!

CBD Bulk Pricing Benefits

Whether you want to sell Joy Organics products at your store or want to enter the Joy Organics White Label Program, you will need CBD oil to start your business. No matter which industry you’re in, everyone gets a discount when they order in bulk from manufacturers. It’s no different with CBD manufacturers.

CBD Manufacturer vs. CBD Company

There is a large difference between CBD manufacturers and CBD companies. If you’re looking to purchase CBD oil products wholesale or for white label CBD products, then you are a CBD company. You are looking for CBD oil suppliers who can help you realize your career goals.

CBD manufacturers are the ones who have the technology necessary to extract CBD oil from the plant. Depending on the manufacturing facility, they can run multiple operations. Understanding these differences is essential for running your business.

Differences in CBD Oil Manufacturers

Before you get too far into vetting potential CBD oil manufacturers, figure out what type of CBD oil products you want to sell. Then, determine if their manufacturing facility can accommodate your requests.

Understanding their technology and extraction methods is important for your bottom line, as these resources will impact the type of products you sell and how much the CBD oil will cost.

For instance, some companies specialize in full spectrum hemp extracts. That’s where all cannabinoids remain in the formula, including THC.

Other manufacturing facilities are capable of removing THC. 0.0% THC products, like Joy Organics’ line of products, are considered broad or full spectrum. Broad spectrum CBD oil requires cutting-edge technology that isolates phytocannabinoids.

Speaking of isolating, you might just need to browse CBD isolate manufacturers. These CBD oil suppliers provide pure CBD to integrate into your line of products.

CBD Companies vs. CBD Suppliers

If you are selling CBD, you are a CBD company. Therefore, some of the largest CBD manufacturers in the world are also the top CBD companies. However, some CBD manufacturers provide top CBD companies with the phytocannabinoids necessary to make their own unique line of products.

Being this type of CBD company is still a great experience. That’s why you might be better suited joining a Wholesale CBD or White Label CBD Products Program. Within this type of program, CBD suppliers give you everything you need to run your own CBD business.

You use their products and resources, but it’s your brand name on the bottle. Your CBD company is free to market what you receive from your CBD oil suppliers however you please!

How Joy Organics Chose CBD Manufacturers

Our mission when starting Joy Organics was to help people live healthier and happier lives. You can’t accomplish this goal with subpar CBD oil suppliers. So, we created a list of standards that potential CBD oil manufacturers had to meet. We are so grateful we found the right team to help bring our vision of premium broad and full spectrum hemp extract to life. Here’s what we looked for in CBD manufacturers.

Proof of an Actual Manufacturing Facility

To date, the CBD industry has been largely unregulated. This means that oil can be extracted pretty much anywhere, and no one would know the difference. When researching various CBD manufacturers, make sure that the product they’re offering is made in a legit manufacturing facility rather than in someone’s garage or shed.

Know CBD Manufacturer + Location of Farm

Once we had potential CBD oil suppliers in mind, we looked at where they sourced their hemp.

We asked the following questions:

  • Is it grown sustainably, using organic practices?
  • Are crops grown in accordance with the highest cultivation standard?
  • Is this a U.S. farm or cultivated overseas?
  • Do they breed high strains of CBD?

Knowing how the hemp is sourced didn’t just tell us about the plant. It told us about the ethics of the CBD oil suppliers. Even state-of-the-art equipment can’t make up for cutting corners with harvests made from inorganic farm practices.

Seed-to-Sale Cycle Tracking

Every minute of a hemp plant’s life cycle denotes critical moments in CBD production. Some people need specific phytocannabinoids that are present earlier in the plant’s life. Others need some of the terpenes that develop later in the cycle.

The more you know about the plants used to make your product, the more targeted approach you can make in creating products and marketing them. That’s why we only considered farms that had seed-to-sale cycle tracking.

Seed-to-sale cycle tracking follows the plant through these stages:

  • Cultivation
  • Harvest
  • Extraction
  • Production
  • Distribution
  • Sales

These tracking systems often contain a combination of written records and software in a single database that can be used by cultivators, processors, manufacturers, transporters, and others involved in the process that provides a thorough history of the product.

Appropriate Regulatory Licenses and Certificates

While CBD has been largely unregulated thus far, there are certain regulatory licenses and proper manufacturing certifications that the best CBD manufacturers will carry. Only the top CBD companies align with these types of manufacturing facilities. We’re no exception!

Now, be careful. Regulatory licenses and certificates will vary from state to state. Trusted CBD manufacturers should be clear about the regulatory licenses they carry.

A few regulatory licenses and certificates to keep an eye out for include:

  • International Organization for Standardization (ISO)
  • Good Manufacturing Process (GMP)
  • Governance and Professional Practice (GPP)

These regulatory licenses and certificates mean that the equipment is in pristine condition. They passed a government inspection and the products they make meet the needs of customers and stakeholders while meeting statutory and regulatory requirements related to CBD.

Certificates of Analysis (COAs)

Each CBD oil batch should be consistent. COAs ensure this quality. These documents provide a thorough breakdown of what is in the hemp extract they’ll be supplying.

Common inclusions on COAs are:

  • Phytocannabinoids (CBD, THC, CBDa, CBN, etc.)
  • Terpenes
  • Pesticides
  • Mold
  • Heavy Metals

Not only do COAs create transparency, but they also ensure that the product contains exactly what it claims. A 2017 study found that almost 70% of CBD products sold online aren’t labeled correctly, having either considerably less or more CBD than advertised. CBD manufacturers should offer the most recent COAs of the products they provide.

5 Reasons to Choose Joy Organics As Your CBD Supplier

Choosing between CBD oil suppliers is a difficult decision. That’s why Joy Organics is making the decision easy. We have everything necessary to set you up for success.

Top CBD companies don’t get where they are without having high-quality products. Our CBD manufacturers implement cutting-edge technology that makes the smallest CBD particles on the market. This process gives our line of 0.0% THC broad and full spectrum products high bioavailability. Plus, our tinctures and jarred salves are now USDA certified organic.

2. Transparent and Consistent

Every batch of our premium-grade products is tested for purity throughout every step of the process. Our lab reports are easy to find on our product pages. We’re so sure that each batch will be the same high quality that every order is backed with a 100% money-back guarantee.

3. Unparalleled Customer Service

Your success is ours. That’s why we partner you with a specialist who will be your sole contact for orders. This practice helps build trust and communication between both partners. We also offer free shipping and dropshipping opportunities to meet your brand’s unique demands.

4. Educational Resources

We learned a lot about the CBD industry while vetting CBD oil manufacturers. That’s why we simplified the information into digestible videos you can use to expand your CBD business knowledge.

5. We Preserve Your Individuality

You and your brand are unique. They should be treated that way. That’s why we use all of our resources to ensure your brand’s voice is never lost. From fonts to verbiage to color combinations, your CBD company will stand out from the rest and capture your brand’s vibe.

CBD Manufacturing FAQs

What Is the Difference between CBD Oil Manufacturers vs. Suppliers vs. Companies?

A CBD oil manufacturer extracts the oil from hemp plants. They will provide a supplier (or distributor) with wholesale CBD oil. These distributors supply CBD companies with the oil needed to manufacture their line of products. Sometimes the CBD oil manufacturer, supplier and company are the same entity.

What to Look for in a CBD Oil Manufacturer?

First, make sure they have an actual manufacturing facility. Heavily vet the manufacturer and their hemp farmers to ensure they use organic ingredients and practices. Only work with companies that use seed-to-sale tracking. CBD oil manufacturers should also have the appropriate regulatory licenses and certificates of analyses to assure purity.

How Do You Get Bulk Pricing for CBD Oil?

Bulk pricing options for CBD oil are dependent on which company you choose as a partner. Common programs that offer bulk pricing discounts include wholesale CBD oil programs, dropshipping programs, or white label programs.

What Is a CBD White Label Program?

A white label program is a business opportunity where you partner with a CBD oil company to promote products under your brand name. As a business owner, you have the autonomy to choose hours, pricing, and marketing strategies.

Why Join a CBD White Label Program?

A CBD white label program is a unique opportunity to earn supplemental income or make a career change. Joining a CBD white label program allows you to profit from a billion-dollar industry with little investment upfront. You are partnering with an established brand that already has the resources you need to succeed.

How Do I Choose a CBD White Label Partner?

The quality of the product is what matters most when choosing a CBD white label partner. Not only will you be selling the supplier’s products, but you will be putting your label on them. Try the product before committing to a partnership. Also, only partner with brands that implement third-party lab testing for purity.

Why Choose Joy Organics as a CBD White Label Partner?

Joy Organics sells a variety of natural CBD oil products that are third-party lab tested for purity. We offer free shipping and low minimum orders on our vast catalog of broad spectrum and full spectrum hemp products. Every partner is assigned a personal account specialist who walks you through everything from choosing a logo to marketing your products. We build personal relationships to ensure your business goals are met!

Are You Ready to Partner with The Leading CBD Manufacturing Company, Joy Organics?

The beauty of partnering with Joy Organics is we did all the hard work for you. We can ensure that the seed-to-sale cycle is within its best-by date, that the CBD manufacturers have all their licenses and certificates, and that we have all of our COAs available for viewing. You can focus on the fun stuff like designing packaging, marketing initiatives, and choosing products.

See also  Solventless CBD Oil

With that peace of mind, you can also focus on your savings. We offer many unique opportunities for growth in our White Label Program, including savings by using blank bottles, low SKU orders, and minimum shipping requirements.

Call us today to chat about our White Label Program. With Joy Organics as your CBD supplier, you can become one of the top CBD companies. We are excited to help that vision happen!

10 Best CBD Companies to Buy From in 2022: Honest Reviews & Guide

To find the best CBD oil companies on the market, we devised a set of criteria that we applied to each brand that we considered.

Once an obscure niche product, CBD is now undoubtedly mainstream. Due to a continuing lack of FDA regulation, however, there are no overarching quality standards in the CBD industry.

Consequently, consumers have to determine which CBD products are high-quality and effective. To make it easier for you to choose CBD oil brands that offer the best value and the safest products, we put together this detailed review of the best CBD brands of 2022 and beyond.

Best CBD Companies Ranked

Other Great Brands

  1. CBDistillery
  2. Charlotte’s Web
  3. Lazarus Naturals
  4. Royal CBD
  5. JustCBD

Which Company Has The Best CBD Oil in 2022?

To find the best CBD oil companies on the market, we devised a set of criteria that we applied to each brand that we considered. Leveraging our own expertise and calling upon the insight of industry experts, we determined the value that each brand in our list provides by thoroughly evaluating the following factors:

1. Brand Credibility

  • How adaptive and well-designed was the brand’s website?
  • How well was their site content written?
  • How quickly did they respond to customer inquiries?

These are just a few examples of the variables we used to determine brand credibility.

2. Hemp Source

U.S. hemp is the highest-quality, and using hemp grown in the United States supports the domestic agricultural economy. Brands that used organically grown hemp cultivated in the United States received the highest grades.

We also took into account factors such as whether a brand’s hemp was U.S. hemp authority-certified or non-GMO. At this point, non-GMO hemp is the standard in the industry, so we disqualified brands that used hemp that was genetically modified.

3. Extraction & Purification

There are a variety of solvents that brands can use to extract CBD from hemp. Some of these solvents are difficult to purge from finished products, however, and they can cause respiratory harm.

Carbon dioxide is widely recognized as the safest extraction solvent for hemp. As a result, brands that use CO2 extraction received high scores, while brands that use butane, ethanol, or acetone extraction were penalized.

4. Lab Reports

In lieu of FDA regulation, third-party lab testing has become the gold standard for determining a hemp product’s safety and quality. CBD products that have been third-party lab tested can be verified as not containing contaminants.

However, there are quite a few different third-party lab test providers on the market, and some are less independent than they seem. In addition to making sure that products were tested, we also looked at which company provided the lab tests for each of the hemp brands we examined.

5. Customer Service

You can learn a lot from how a CBD brand handles its customer service. Obviously, customers are better served by brands that respond quickly and offer courteous customer service.

If a CBD brand’s customer service is lackluster, however, that brand might also be lacking in other ways. We checked each brand’s customer service capabilities to determine its overall integrity and attention to detail.

How Our Experts Chose These Criteria

We’re no strangers to the CBD industry. We’ve watched interest in CBD grow over the years, and we’ve observed the highest and lowest points in the industry’s history.

Over time, the experts who put together this guide have had plenty of chances to compare and contrast CBD companies. We’ve seen which companies have risen to the top, and we’ve seen how they achieved these results.

At the same time, we’ve become familiar with the most common points of failure within the CBD industry. We developed our evaluation criteria based on longitudinal research into the brand factors that are most likely to result in high-quality CBD products.

Best CBD Companies: Detailed Reviews

Colorado Botanicals: Best All-Around & Highest Quality

After extensively considering each brand’s benefits and drawbacks, we determined that Colorado Botanicals offers the best products for the most reasonable prices. This brand offers similar product types to major competitors, but it enhances these products’ benefits by tapping into the hemp plant’s true potential.

Brand Credibility

Colorado Botanicals isn’t a household name, but the company more than holds up against its bigger competitors. Every aspect of the Colorado Botanicals brand met our strict criteria for excellence.

  • Clean, simple website with excellent graphics
  • Detailed product information and site content
  • Highly detailed third-party testing reports
  • Broad-spectrum, THC-free CBD products
  • Extensive focus on the benefits of terpenes

Colorado Botanicals also won our top spot for Best CBD Oil and Best CBG Oil of 2022, proving that quality – not famous branding – determines a product’s success.

Extraction & Purification Standards

Colorado Botanicals uses CO2 extraction to produce its Full and Broad-Spectrum CBD oil products. Using an advanced distillation process that leaves terpenes intact while removing all traces of THC, Colorado Botanicals produces high-quality Broad-Spectrum distillate.

This distillate does not contain waxes, chlorophyll, or unnecessary lipids. It has a mild taste that is made even more pleasant by its high terpene content.

Type of CBD

Most of Colorado Botanicals products are Broad Spectrum but they started offering Full Spectrum CBD oils. In contrast with Full-Spectrum CBD oil, this type of purified and refined CBD is entirely THC-free, assuaging potential concerns regarding THC contamination in CBD products.

What’s most impressive about Colorado Botanicals products is their high terpene concentrations. Often overlooked in the CBD industry, terpenes are beneficial substances found in Cannabis sativa that each has unique properties.

Focus on Terpenes

It’s important to note that the terpenes found in Colorado Botanicals Full and Broad-spectrum CBD oil are not reintroduced into the finished product. Instead, they are the original terpenes present in the CBD-rich hemp flower that Colorado Botanicals naturally retains.

Reintroduced terpenes can cause contamination issues, and they don’t provide the same effects as terpenes that are naturally present in CBD extract. We’re impressed that Colorado Botanicals knows the difference and their ability to naturally retain terpenes in its products.

About Terpenes

Why are terpenes so important? Scientists believe that terpenes may contribute to the entourage effect , which is a theorized form of Cannabis sativa synergy that may occur when cannabinoids and terpenes are used together.

Initially believed to primarily apply to interactions between cannabinoids, researchers have now recognized that terpenes may be just as essential to the activation of the entourage effect. CBD products that contain terpenes may be more effective or provide more benefits than products that do not.

Individual Effects of Terpenes

In addition to potentially contributing to the entourage effect, terpenes also have individual benefits. Found in many other plants aside from Cannabis sativa, terpenes have been studied for decades for their potential beneficial effects.

  • Beta-Caryophyllene – Beta-caryophyllene is one of the only terpenes that acts like a cannabinoid. It stimulates the nervous system’s CB2 receptors , which modulate inflammation. Unlike CB1 receptors, CB2 receptors do not cause intoxication. However, these neuroreceptors have dozens of potential beneficial effects aside from their observed impact on inflammation.
  • Humulene – Like most terpenes, humulene has been studied for its potential antioxidant and anti-inflammatory effects. Humulene is also one of a few terpenes that have been researched for their potential antimicrobial benefits .
  • Linalool – Along with humulene, linalool has been studied for its potential antimicrobial and antioxidant benefits . This terpene is found in lavender as well as hemp.
  • Bisabolol – A rare terpene, bisabolol has been studied for its potential ability to reduce skin inflammation , and the antimicrobial potential of this terpene has also been researched.

Terpene Lab Tests

To give you an idea of just how seriously Colorado Botanicals takes terpenes, here are the results from one of this brand’s recent lab tests:

Since testing for terpenes is an added service, most CBD brands fail to determine the exact concentrations of terpenes present in their products. Colorado Botanicals, on the other hand, makes sure that their third-party lab tests contain detailed terpene information.

Price per Milligram of CBD

The price per milligram of CBD varies among Colorado Botanicals products. We’ll use this brand’s 1500mg CBD tincture as a baseline, however, since many brands produce similar tinctures.

This product presently costs $110, so the CBD in this tincture costs $0.073 per milligram. This price is standard within the industry, and Colorado Botanicals tinctures offer added value due to their terpene content.

Lab Reports

Colorado Botanicals lab reports are available in PDF form in a public Google Drive folder that is linked on each product page. They test their products and extracts at FESA Labs and ProVerde Laboratories. They provide detailed information on the cannabinoid, terpene, and contaminant concentrations present in each product.

Customer Support

In our experience, Colorado Botanicals offered excellent customer support. This brand provides a contact form, email address, and phone number you can use to get in touch with customer service.

A representative answered the phone immediately when we called. We received a response to an emailed inquiry on the same day.

Certifications

Colorado Botanicals has received ISO 9001:2015 certification for its production facility. This brand uses cGMP processes to produce its products.

Pros & Cons

Here are the highs and lows of this exemplary CBD brand:

Pros

  • Broad-spectrum, THC-free CBD
  • Offers Full Spectrum CBD Oil now
  • Terpene-rich CBD extract
  • No reintroduced terpenes
  • Reasonable price-per-milligram
  • Detailed lab reports with lab reports page
  • ISO 9001:2015 certification
  • The best customer service we’ve come across in all the audits we did

Cons

  • Products aren’t significantly more affordable than options offered by competitors
  • Shipping is free over $74

Bluebird Botanicals: Best Full-Spectrum

Bluebird Botanicals has been around since 2012, and this brand is still going strong. While the quality of the full-spectrum and CBD isolate products Bluebird Botanicals offers certainly seems satisfactory, we were more impressed by this brand’s prices.

If you’re looking for quality CBD that’s lighter on the wallet, this is probably the best option. Normally, low price a red indicating poor quality. Bluebird Botanicals, however, proves that there are major exceptions to that rule.

Brand Credibility

Any CBD brand that’s been around for more than eight years carries plenty of clout. While the Bluebird Botanicals website was relatively cluttered, it contained plenty of helpful information, and this brand is highly transparent regarding where it sources its hemp and how it produces its products.

Extraction & Purification Standards

Bluebird Botanicals uses a mix of CO2 extraction and ethanol extraction. This brand then uses steam distillation to remove impurities from its extracts. It’s unclear why Bluebird also uses ethanol if this company also has access to CO2 extraction facilities.

Type of CBD

Most of the products Bluebird Botanicals offers include Full-Spectrum CBD. In contrast with Nuleaf, Bluebird uses distillation to remove impurities like chlorophyll from its CBD oil.

However, Bluebird leaves traces of THC behind in its extracts instead of choosing to produce Broad-spectrum CBD. To boost its lineup with THC-free products, Bluebird also provides a few offerings that contain CBD isolate.

Price per Milligram of CBD

Bluebird’s Extra Strength Classic CBD Oil tincture contains 1500mg CBD, and it costs $99.95. As a result, this product’s price-per-milligram is $0.066, making Bluebird Botanicals CBD highly affordable.

Lab Reports

Instead of linking to lab reports on product pages, Bluebird provides them all on a single page, making it difficult to access the report you’re looking for. This brand breaks its third-party lab results into multiple sections, making the process a bit more confusing.

However, Bluebird tests for terpenes, heavy metals, mycotoxins, and a variety of other variables. Even though the reports may be difficult to access, this brand’s lab reports are among the industry’s most thorough.

Customer Support

We found Bluebird’s customer service team to be highly accessible and responsive. This brand provides a contact form, a phone number, and multiple email addresses.

Certifications

Bluebird Botanicals has received a number of certifications, including:

  • B Corporation Certification
  • Leaping Bunny Cruelty-Free Certification
  • U.S. Hemp Authority Certification
  • Glyphosate Residue Free Certification

It does not appear, however, that Bluebird’s production facilities have been ISO certified.

Pros & Cons

Here’s what we liked and disliked about Bluebird Botanicals

Pros

  • An industry veteran with a great reputation
  • Highly certified brand
  • Detailed lab reports
  • Quality products

Cons

  • In THC-free products, CBD isolate is used instead of broad-spectrum CBD
  • Lab reports are hard to find
  • The website is somewhat cluttered

Nuleaf Naturals: Best By Reviews

Full-spectrum CBD can be hit-and-miss, but some CBD users swear by the benefits of Full-spectrum products. With more than 20,000 reviews, Nuleaf Naturals is the most popular provider of Full-spectrum hemp products on the market, and we like the simplicity of this brand’s product lineup.

We noticed positive effects and why it landed so high on the list despite the high cost it comes at.

Brand Credibility

Nuleaf Naturals is highly regarded, and this brand’s website is clean and simple. It’s hard not to feel like a brand has credibility when it has accumulated so many positive customer reviews.

Extraction & Purification Standards

Nuleaf uses CO2 to extract its CBD, further improving our impression of this brand. This brand uses a type of Full-Spectrum oil called winterized CBD, which is more raw than refined.

Type of CBD

Nuleaf Naturals products contain winterized Full-Spectrum CBD, which might appeal to some consumers since it’s so raw and unrefined. Winterized extract, however, contains waxes, chlorophyll, and other substances that might taste unpleasant or impair ingestion.

Price per Milligram of CBD

Nuleaf Naturals offers 1,800mg Full-Spectrum tinctures for $179. As a result, this brand’s CBD costs around $0.099 per milligram, one of the industry’s highest prices.

Lab Reports

Nuleaf’s lab reports are hard to find, and they aren’t product-specific. However, this brand’s third-party testing is provided by Botanacor, a reputable lab.

Customer Support

Nuleaf provides customer support via phone, email, and contact form. Our call was answered immediately since we called during business hours, but it took around 24 hours to receive a response to our email.

Certifications

Nuleaf Naturals doesn’t provide information regarding any certifications this brand might hold.

Pros & Cons

Here are what we considered to be the highs and lows of Nuleaf Naturals:

Pros

  • Offers some of the best full-spectrum CBD on the market
  • Over 20,000 satisfied customer reviews
  • Simple, clean website, & very easy to use
  • Been around for a long time and have built trust

Cons

  • High CBD price per milligram
  • They use Winterized CBD Extract so it isn’t purified like a distillate but winterized extracts do generally contain higher amounts of plant compounds which can be good and bad if not purified properly.
  • Lab results are vague and hard to find

Medterra: Highest Concentration

With more than 5,000 customer reviews, Medterra is one of the nation’s most popular CBD oil brands. The quality of Medterra’s CBD was exceptional, and we did like the cannabinoid content of their oil. They did contain higher amounts of cannabinoids than usually seen in CBD products. However, they didn’t test for terpenes, which doesn’t clarify if their extracts contain the terpene contents like Colorado Botanicals.

When testing out their CBD oil, we did notice it to be one of the most effective ones from this list, hence why we ranked it number 2 out of 10.

Brand Credibility

Medterra is certainly one of the most credible CBD oil brands. This company’s site content is on-point, and Medterra provides plenty of information on each of the products it produces.

Extraction & Purification Standards

Medterra uses CO2 extraction to produce its products. Based on customer reviews and our own research, Medterra CBD is highly purified, and it doesn’t contain any waxes, excess lipids, or chlorophyll.

Type of CBD

Medterra used to offer Full-Spectrum CBD oil products. Nowadays, however, this brand only produces Broad-Spectrum CBD and CBD isolate products.

Price per Milligram of CBD

Medterra offers a 1000mg Broad-Spectrum CBD tincture for $59.99. As a result, this brand provides a CBD price-per-milligram of only $0.059, which is one of the lowest prices found in the industry.

Lab Reports

Third-party lab reports from Green Scientific Labs are easy to find on each Medterra product page. While these reports include results for dozens of solvents and pesticides, they do not include results for terpenes.

Unfortunately, it does not appear that Medterra takes the benefits of terpenes very seriously. This lamentable perspective is also clear to see in Medterra’s CBD isolate products, which don’t contain any terpenes whatsoever.

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Customer Support

Medterra offers a live chat service. In our experience, however, customer service agents are rarely available for live chat. Instead, customers can contact Medterra by phone, email, or contact form.

Certifications

Medterra products are U.S. hemp authority-certified. However, this brand does not provide any information certifications it may have achieved for its production facilities.

Pros & Cons

Here are the key advantages and disadvantages of Medterra’s products:

Pros

  • Affordable products
  • Over 5,000 customer reviews
  • Easily accessible lab reports
  • Ultra Broad Spectrum CBD Oil has great cannabinoid profile
  • Offers Immune Boost CBD Oil that holds other ingredients

Cons

  • The benefits of terpenes are overlooked
  • Somewhat cluttered product catalog

cbdMD: Best Price

cbdMD is known for its prominent partnerships with athletes and other celebrities. The cbdMD website is remarkably well-built, and this brand produces informative content.

This brand’s products are pretty decent. But while it may not stack up to the above vendors, cbdMD still offers the best price we’ve seen so far. cbdMD also beats its competitors in terms of potency, with up to 7,500mg of CBD in a 30mL bottle.

Brand Credibility

cbdMD operates one of the best CBD eCommerce websites we’ve seen. This brand’s site loads quickly, and it’s full of informative content.

Extraction & Purification Standards

cbdMD uses CO2 extraction to produce its crude hemp extracts. While cbdMD doesn’t provide any information directly stating how it refines its extracts, we assume that this brand uses steam distillation.

Type of CBD

cbdMD products contain Broad-Spectrum CBD extract, though it’s hard to discover this fact without considerable research. This brand sources its hemp from farms located in the United States.

Price per Milligram of CBD

cbdMD offers a 1500mg tincture for $99.99. As a result, this product has a price-per-milligram of $0.067, which is relatively standard within the industry.

Lab Reports

We were very impressed with the procedure cbdMD uses to provide lab reports to consumers. First of all, this brand’s lab reports are conducted by SC Laboratories, one of the nation’s most respected independent labs.

There’s a huge, highlighted button on every product page that you can use to load cbdMD’s lab reports. These reports appear as a popup window, and there are buttons you can use to either download or print the lab report for a particular product.

cbdMD’s lab reports are remarkably detailed, but they reveal that this brand’s products don’t contain considerable concentrations of terpenes. We wish that cbdMD provided lab report archives, not just the results of the latest test.

Customer Support

cbdMD customer support is reachable by live chat, email, contact form, and phone. We found cbdMD’s email support agents to be responsive and helpful.

Certifications

In 2020, cbdMD received NSF International Good Manufacturing Practice (GMP) registration. This certification confirms that cbdMD’s production facilities adhere to the latest cGMP standards. cbdMD is also a member of the U.S. Hemp Roundtable.

Pros & Cons

Here’s a brief summary of the highs and lows of cbdMD:

Pros

  • Big, professional brand with a well-designed website
  • Reasonably priced products
  • Excellent, informative lab reports
  • Wide variety of products to choose from

Cons

  • We didn’t find the pet products to be effective as other pet products we’ve reviewed in the past

Honorable Mentions: Other Great CBD Brands

CBDistillery

We’ve been fans of CBDistillery ever since this brand only offered CBD isolate. Some things about CBDistillery have certainly improved over the years.

In terms of the quality and effectiveness of their oil, we found it effective but not quite enough to be at the top of this list, However, it is a great company to consider purchasing and trying.

Brand Credibility

In our opinion, CBDistillery is a credible company and is well-known in the CBD industry. One thing we noticed is that their lab reports were not easily accessible – they promote third-party testing as a priority.

At the same time, CBDistillery’s website is remarkably responsive and well-designed, and it’s populated with elegant, convincing content. CBDistillery is certainly one of the nation’s biggest CBD companies, which has forced this brand to be reasonably accountable.

Extraction & Purification Standards

CBDistillery uses CO2 extraction to produce its crude CBD extracts. Then, this brand uses steam distillation to produce high-purity isolates and distillates.

Type of CBD

CBDistillery offers a wide selection of Full-Spectrum, Broad-Spectrum, and Isolate CBD products. This brand’s catalog is well-rounded, but CBDistillery offers so many different products that it can be hard to zero in on an ideal formulation.

Price per Milligram of CBD

CBDistillery offers a 1000mg full-spectrum CBD tincture for $60. As a result, the price-per-milligram for this product is $0.06. Like most brands, CBDistillery progressively discounts its higher-dosage products.

Lab Reports

We were unable to find CBDistillery’s lab reports. While this brand claims its products are third-party lab tested, we couldn’t find them with a Google search.

Customer Support

CBDistillery offers a live chat, and this brand is also available by phone and contact form. We found CBDistillery’s customer support to be relatively engaging and responsive.

Certifications

We weren’t able to find any information on certifications that CBDistillery might possess.

Pros & Cons

Let’s summarize the high and low points of CBDistillery:

Pros

  • Veteran brand that has expanded significantly
  • Lots of product options
  • Competitive price-per-milligram
  • Great information easily accessible on their website for new CBD users who wouldn’t mind reading up on them

Cons

  • You have to complete a “Money-Back Guarantee Form” in order to get a refund
  • Third-party lab reports were missing

Charlotte’s Web

Charlotte’s Web rose to fame as one of the first CBD companies to directly target childhood epilepsy. Launched in 2011 as one of the earliest CBD brands, they became popular after helping a little girl named Charlotte Figi. She suffered from Dravet Syndrome, which is a rare form of epilepsy.

Her first seizure occurred when she was just three months old, which was said to have lasted a full 30 minutes. As she grew older, it worsened with multiple seizures per day, and doctors told the parents there was nothing they could do.

Or was there? When the family became introduced to cannabis and CBD, Charlotte’s Web owners, the Stanley brothers, who owned a cannabis dispensary, began supplying products to their family.

Charlotte Figi, who suffered from life-threatening seizures, saw considerable changes in her body as she continued to use the cannabis extract oil that the Stanley Brothers produced. Soon after seeing the positive impact it had on her life, the brothers decided to change the name to Charlotte’s Web in honor of her.

As CBD regulations have evolved, Charlotte’s Web has pivoted to offer a wide range of general-purpose CBD products.

In terms of their CBD oil and products’ quality, we didn’t find it as effective as the other brands listed here. They have a vast customer base and long-time customers, but we think that their customers will move over to other brands if they don’t improve their extracts’ quality.

Their CBD gummies did taste amazing, and we’re one of the more effective CBD gummies we’ve tried. If you’re looking for good-quality sleep gummies with melatonin, then we would highly recommend giving theirs a try.

Brand Credibility

At a glance, Charlotte’s Web website is well-built and content-rich. Charlotte’s Web bills itself as “the world’s most trusted hemp extract,” but it’s unclear whether this brand is also the world’s most trustworthy CBD producer.

Extraction & Purification Standards

Charlotte’s Web uses a combination of CO2 and isopropyl alcohol extraction techniques. It’s unclear why this brand doesn’t simply stick to CO2 extraction, which is cleaner and more reliable.

Type of CBD

Charlotte’s Web products include Full-Spectrum CBD extract. This brand doesn’t provide any information regarding whether its extracts are distilled or crude.

Price per Milligram of CBD

Charlotte’s Web uses creative measurements that make it relatively difficult to determine how much CBD is contained in each bottle of this brand’s tincture. However, after running some calculations, we’ve determined that Charlotte’s Web offers an 1800mg tincture for $119.99, which is priced fairly.

As a result, this product offers a price-per-milligram of $0.067. This price is standard.

Lab Reports

Charlotte’s Web makes it difficult to access lab reports for its products. You have to input the lot number for your product, which is only available on the product’s outer packaging. If you’re trying to look at their lab reports to help determine if you want to purchase over another brand, you won’t be able to.

Furthermore, Charlotte’s Web does its own in-house lab testing. Charlotte’s Web is the only major CBD brand we’re aware of that breaks from conventional testing in this way.

Customer Support

Charlotte’s Web customer service was reasonably responsive. You can contact this brand via live chat, contact form, or phone.

Certifications

Charlotte’s Web is a certified B Corporation.

Pros & Cons

Let’s summarize the best and worst aspects of Charlotte’s Web:

Pros

  • Reasonably priced products
  • Certified B Corp
  • Wide variety of products to choose from including Sleep Gummies, Recovery Gummies, & Calm Gummies.
  • Sleep gummies we’re very effective

Cons

  • No third-party lab reports, and lab reports are very difficult to access
  • Mixture of isopropyl alcohol and CO2 extraction methods
  • Long shipping times

Lazarus Naturals

There’s a lot we like about Lazarus Naturals. This brand exudes a down-to-earth, working-class mystique, and it features high-quality, organic products that appeal to sustainability-conscious consumers.

At the same time, Lazarus Naturals’ headlong focus on wholesale relationships has allowed this brand’s direct-to-consumer side of operations to suffer. The Lazarus Naturals website is relatively slow, and it’s hard to find pertinent information on this company’s products.

In terms of the quality of their CBD oil, we found it to be effective. They also have many long-time loyal customers, which explains a lot.

Brand Credibility

As a major CBD brand, Lazarus Naturals can’t help but be reasonably credible. Most of this brand’s products have a few dozen reviews, and the content featured on lazarusnaturals.com is convincing. We wish that Lazarus would make its product catalog more accessible to consumers.

Extraction & Purification Standards

Lazarus Naturals uses ethanol to produce its crude CBD extract, which is a low-cost option that many brands opt for. From there, this brand uses steam distillation to remove residual solvents, chlorophyll, and other undesirable substances.

Ethanol extraction is inferior to CO2 extraction.

Type of CBD

Lazarus Naturals offers a wide range of full-spectrum and CBD isolate products. The fact that this company does not offer any Broad-Spectrum CBD products casts doubt on the thoroughness of its extract purification process.

With modern distillation methods, it’s relatively easy to make broad-spectrum CBD. It’s possible that Lazarus is using an outdated form of distillation that might offer decreased product purity.

Price per Milligram of CBD

Lazarus Naturals offers a 15ml, 750mg CBD isolate tincture for only $24. This brand is kind enough to provide the price-per-milligram for this product directly on its product page: $0.032.

That’s one of the lowest, if not the lowest price-per-milligram we’ve ever seen. Rather than inspiring confidence, this rock-bottom price makes us wonder what Lazarus Naturals is sacrificing to keep costs so low.

Lab Reports

Third-party lab reports for Lazarus Naturals products are easy to find on every product page. This brand’s lab reports are provided by Columbia Laboratories, a little-known Portland, OR, analytics lab.

Customer Support

Lazarus Naturals is easy to reach by phone or email. We found this brand’s customer service agents to be responsive and helpful.

Certifications

Lazarus Naturals recently upgraded to a 40,000 square foot production facility in Portland. This brand’s new facility is cGMP-certified.

Lazarus Naturals products are also certified kosher. This is a step that other brands usually choose not to take even though almost all CBD products are inherently kosher.

Pros & Cons

Here’s a brief summary of the best and worst aspects of Lazarus Naturals:

Pros

  • Focus on sustainability and organic ingredients
  • Lab tests are third-party, recent, and easy to find
  • Price-per-milligram is very low

Cons

  • Website is relatively cluttered and difficult to navigate
  • Indirect evidence suggests that purification methods may be sub-par

Royal CBD

One of the first things you’ll see on Royal CBD’s website is “no room for mediocrity.” It’s a catchy and intense slogan that the vendor strictly follows.

An excellent source of Full-Spectrum and Broad-Spectrum CBD products, the company sources its extracts from organic, non-GMO hemp.

Brand Credibility

Royal CBD has a smaller online presence than bigger players like Lazarus Naturals or cbdMD. Still, the company boasts a respectable 2700 customer reviews listed on its website.

Royal CBD also deserves points for its well-written blog filled with plenty of relevant information for new CBD users. This resource undoubtedly makes it easier to choose the right product.

Extraction & Purification Standards

Royal CBD uses CO2 extraction to make its products, which leaves behind no trace solvents. But purity always starts at the source, which is why Royal gets its extracts from organically-grown, non-GMO Colorado hemp.

Type of CBD

Royal CBD exclusively offers full-spectrum CBD oils. However, they offer a Broad-Spectrum extract option in their line of gummies.

Price per Milligram of CBD

Royal CBD is one of the priciest brands we’ve seen (although there are some reasons why this is justified). Still, it’s a substantial investment.

For example, their highest concentration of 2500mg offers the best value per milligram. Although currently on sale for $229.00 as of the writing of this review, the original retail price is $289.00. This translates to about $0.12/mg.

That’s a huge price difference, considering our leading choice, Colorado Botanicals, sells a 3,000mg tincture for $199.99, or about $0.07/mg.

Lab Reports

Royal CBD repeatedly states that they perform third-party lab tests available to the public. However, after searching the site’s product pages, FAQ, and navigation tabs – along with a separate Google search – no links to these alleged results were listed.

Customer Support

Royal CBD offers customer support through phone or a generic contact form. Having a chat feature, however, would be helpful for quick, convenient answers.

Certifications

No information is available about any certifications or professional memberships Royal CBD may have.

Pros & Cons

Like all vendors, Royal CBD excels in some areas more than others.

Pros

  • Up to 83mg/ml
  • Organic
  • CO2 extracted
  • 15% subscription discount

Cons

  • Unable to find third-party lab reports
  • Terpenes are added after extraction
  • Very expensive compared to other CBD brands

JustCBD

“JustCBD” is a bit of a misnomer, given that the company offers the biggest variety of CBD products on our list. Aside from oils, creams, capsules, and edibles, JustCBD also sells products like vape juice and cartridges; bath bombs, honey sticks, and the new (albeit controversial) delta-8 THC.

It’s clear that, while the other companies on our list are health-focused, JustCBD caters to a broader audience with a range of therapeutic goals and strategies.

Brand Credibility

JustCBD doesn’t have a huge presence in the CBD community. However, it still has plenty of valuable blog posts with useful CBD-related guides and information. Unfortunately, we did catch them using Wikipedia as a source to describe the entourage effect in their FAQ section. On the other hand, we noticed some of their content is reviewed by a licensed medical doctor.

Extraction & Purification Standards

Extraction methods depend on the product. JustCBD’s Full-Spectrum oils use CO2 extraction. Their tinctures, on the other hand, are processed using alcohol to make them soluble with food and drinks.

Type of CBD

JustCBD offers two liquid options. Customers can choose between two CBD tinctures and a single Full-Spectrum CBD oil product.

Price per Milligram of CBD

JustCBD provides some of the best value on the market. Their 5,000mg 60oz bottle offers the highest concentration, at 83mg/ml.

With a retail price of only $144.99, this Full-Spectrum oil comes to about $0.01/mg. If you take advantage of their 30% discount on repeat orders, the price per milligram dips down to a fraction of a penny.

Lab Reports

JustCBD third-party tests its products. You can quickly find the results using your oil’s batch/lot number. There’s also the option to search by product category.

Customer Support

Clients can contact Customer Care through e-mail or phone. There isn’t a lot of information about the caliber of their service. But the handful of reviews on Trustpilot are mostly positive, with a couple of bad experiences.

Certifications

No information is available about any certifications or professional memberships.

Pros & Cons

JustCBD has a long way to go, with some strong selling points and a few opportunities for improvement.

Pros

  • 30% discount on repeat orders
  • Organic
  • CO2 extracted (full-spectrum oil)
  • Cheaper than any CBD product so far
  • Third-party tested

Cons

  • Offers delta-8 THC, which has been criticized by medical experts for its toxic extraction process
  • Has been the subject of two class-action lawsuits

How Our Experts Chose the Best CBD Oil Brands of 2022

Toward the start of our guide, we provided some basic information on how we chose the criteria we used to grade each of the brands we examined. Then, with each brand review, we provided more detail on what made particular brands stand out and receive high grades.

We need to go into a little more detail, though, regarding how we came across and ended up choosing the winners in our list. Let’s examine the various methods that our experts used to find out which CBD oil brands offer the best products in the industry:

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Customer Reviews

We’ve seen hemp companies brag that they offer the best CBD in existence. We’ve come across almost ludicrously arrogant marketing material and claims that couldn’t possibly be true.

That’s how we learned that sometimes, you need to take a look at reviews from actual customers to determine the quality of a CBD product. We’ll be honest, however, not even customer reviews are perfect.

Selective Reviewing

Unlike eCommerce giants like Amazon and Walmart, which are managed by third parties, CBD brands operate their own eCommerce websites. As a result, they’re able to remove reviews they don’t like.

  • The overall number of reviews a CBD product has received
  • Common themes listed in reviews
  • How reviews compare between brands

Expert Testimony

We’ve developed considerable in-house expertise when it comes to vetting CBD brands. At the same time, we know enough to know that we don’t know everything, which is why we used outside sources to back up some of our research.

To select the best CBD oils on the market today, we consulted with veteran consumers, popular CBD reviewers, and medical doctors. In some cases, we also took what brands had to say about themselves into account.

Original Research

We primarily determined which brands were worth our time by relying on our own research. Having determined a few essential criteria that separate good CBD products from bad, we did original research, and later parsed out our results into the more detailed criteria we’ve listed with each brand we reviewed.

Website Experience

You can learn a lot about a CBD brand within the first three seconds of navigating to its website. These days, there’s no excuse for a website to take longer than three seconds to load.

  • Clutter – If a CBD website was cluttered, visually confusing, or looked like it had been designed in 2004, we moved on immediately.
  • Content – A few spelling or grammatical errors here or there are to be expected. CBD entrepreneurs usually aren’t professional writers, after all. If the content on a website was offensively bad, however, or if it contained blatant claims (CBD cures ALL cancer. ), we knew we weren’t dealing with a reputable company.
  • Mobile-Responsiveness – Wow, this website looks great! Now, load it on your mobile device.

If elements overlap, it’s hard to find the menu, or images are too big, that site that looked so beautiful on a desktop isn’t properly mobile-responsive. Considering the fact that nearly 54% of eCommerce sales are expected to be completed on mobile devices in 2022, mobile optimization is no longer optional.

Brand Responsiveness

We already talked about each brand’s customer support in our reviews. Brand responsiveness, however, is slightly more complex than simply how quickly a brand responds to emails.

  • How developed is this brand’s social media presence?
  • How easy is it to contact that brand?
  • Does this brand offer its email or just a contact form?

These are examples of the questions we asked to determine each brand’s overall responsiveness.

Transparency

CBD companies have learned that they have to provide test results and other detailed product information if they want to succeed. How easy they make it to find this information, however, is up to each brand.

We preferred companies that went out of their way to provide as much information as possible on their products and processes. We avoided companies that made you work to learn what you needed to learn about their products’ quality and reliability.

Value

Value is more complex than simply how much each mg of CBD in your tincture costs. If a brand offers a cheap product, for instance, but makes customer service and returns impossible, for instance, it doesn’t actually provide high value.

This was perhaps the most important factor we considered as we assembled the 10 best CBD oils in this list. By evaluating dozens of different variables, we did our best to select the best overall value companies.

What You Should Know About CBD in 2022

Even though you’re now familiar with the 10 best CBD oil companies on the market, there’s still so much to learn about this non-intoxicating cannabinoid and what it has to offer. In this guide, we’ll provide more information on what CBD does and how to use CBD for a wide range of purposes.

What is CBD?

CBD is short for cannabidiol and is the most abundant active compound found in hemp, while THC is the most in marijuana.

CBD is just one of the 100+ cannabinoids found in hemp and marijuana. Other cannabinoids found in small amounts are Cannabigerol (CBG), Cannabinol (CBN), and Cannabichromene (CBC) to name a few that are similar to CBD but act on different receptors.

  • Isolated in 1940 but identified in 1963.
  • Safe and non-addictive substance.
  • It does not produce a “high” like Tetrahydrocannabinol (THC).
  • CBD can cause side effects such as dry mouth, diarrhea, reduced appetite, drowsiness, and fatigue.
  • CBD works by interacting with multiple receptors in our body that produces different effects.
  • CBD can interact with other medications when taken together since it gets broken down by the CYP450 enzyme that many prescription medications do.

How Does CBD Work?

According to a recent op-ed published in Cannabis Science and Technology, CBD may interact with your body in more than 20 distinct ways. However, scientists have recognized that the most important effects of CBD take place at two specific neuroreceptors.

For instance, researchers have closely researched the activity of CBD at the 5-HT1A receptor , which is the body’s most abundant serotonin receptor. Serotonin is responsible for dozens of critical bodily processes ranging from metabolism to mood regulation.

Scientists have also studied the effects of CBD at the TRPV1 receptor , which is involved in pain, inflammation, and epilepsy. CBD appears to exert the majority of its effects via these two biochemical interactions.

Does CBD Get You High?

CBD does not stimulate the CB1 receptor, which is the component of the endocannabinoid system that causes THC to make you feel high. Instead, CBD acts as an inverse agonist at this receptor, making it harder for your CB1 receptors to bind with THC.

As a result, CBD does not make you feel high. On the contrary, this cannabinoid usually produces a mild, non-intoxicating sense of relaxation.

Does CBD Have Side Effects?

The latest research on this subject , dating to 2019, indicates that CBD does not have any significant side effects. This cannabinoid is also remarkably non-toxic.

A few years ago, reports circulated that CBD causes liver damage. The study responsible for these reports was proven faulty, and its results have never been replicated.

Benefits of CBD

Scientists have researched the potential benefits of CBD for a wide range of diseases and conditions. Here are some examples:

Research into CBD for pain & inflammation

Both the 5-HT1A and TRPV1 receptors are involved in the sensation of pain. This year, researchers published a new study regarding the potential analgesic and anti-inflammatory properties of CBD, and efforts are ongoing to determine the exact analgesic potential of this non-intoxicating cannabinoid.

Research into CBD for depression & anxiety

Both depression and anxiety are largely modulated by the 5-HT1A receptor. In 2015, researchers took a deep dive into the potential antidepressant and anxiolytic properties of CBD, and research into this potential application of CBD is ongoing.

Research into CBD for sleep

Scientists are curious if the benefits of CBD may help you get to sleep at night. In 2019, for instance, a clinical study was conducted to determine the potential connection between CBD, anxiety, and sleep.

Research into CBD for cardiovascular health

Most types of cardiovascular disease are caused by either oxidative stress or inflammation. As a result, scientists have looked into the potential connections between CBD and cardiovascular health . While inconclusive at present, research into the potential cardiovascular benefits of CBD is ongoing.

Types of CBD Products

There are a few different ways to take CBD, and each ingestion method affects your body differently. Familiarize yourself with the four most common ways to use CBD:

Orally ingested CBD

CBD products that you chew up or swallow are considered orally ingested. Examples of orally ingested CBD products include capsules and gummies. While these CBD products are convenient and offer long-lasting effects, they have reasonably low bioavailability.

Sublingually ingested CBD

Because you hold CBD tinctures under your tongue before swallowing, these CBD products are considered sublingually ingested. Like orally ingested CBD, CBD tinctures end up in your digestive tract, but they have a chance to absorb through the thin membrane under your tongue before they enter your gut.

Topically applied CBD

Any CBD product you put on your skin is a topically applied CBD product. Types of topically applied CBD oil products include salves, lotions, and creams, and these products provide benefits in the area where they are applied.

Inhaled CBD

CBD flower and CBD vape cartridges are examples of inhaled CBD oil products. These products offer fast-acting, intense effects, but their benefits don’t last as long. Additionally, you should always exercise caution when allowing substances into your lungs.

How Much CBD Should I Take?

At present, there are no official guidelines regarding how much CBD you should take. Since this cannabinoid is non-toxic, non-intoxicating, and non-addictive, however, feel free to experiment as you determine which CBD dose is right for you.

As a general rule, you should start with a small CBD dose and increase the amount you consume as needed. Keep in mind that, since orally ingested CBD has low bioavailability, you might want to ingest more CBD per session if you use CBD capsules or edibles.

A good CBD dose to start with is 10mg to 20mg for the first 3 to 5 days to test your tolerance levels.

If you don’t feel noticeable effects from that dosage, increase your dose by 5mg to 10mg of CBD every 2 to 3 days to find your optimal dosage.

You may also start with higher doses, which is fine, but it’s essential to know that you may not notice the same effects after a couple of days or sometime after taking high doses. That’s just because you built a tolerance for CBD, and you should take a 3-5 day break from taking any CBD to reset your tolerance levels.

CBD FAQ for 2022 & Beyond

Let’s wrap up with some answers to common CBD questions:

1. Full Spectrum, Broad Spectrum, or CBD Isolate?

What is Full Spectrum CBD Oil?

Full Spectrum is a term used to describe a CBD hemp extract that contains a combination of cannabinoids, terpenes, flavonoids, and other plant oils that are extracted out of hemp. A key feature of Full Spectrum extracts, other than that it contains other compounds than just CBD, holds up to 0.3% THC per gram (1,000mg) of extract.

What is Broad Spectrum CBD Oil?

A Broad Spectrum extract is very similar to Full Spectrum, except they separate the THC using a chromatography system making it THC-Free. This type of product will show no detectable THC levels, and it’s so low that even at very high doses, it won’t cause any psychoactive effects.

What is CBD Isolate?

CBD Isolate is a white crystalline powder form of CBD that is usually 99.8% to 99.9% pure CBD. This type of CBD extract doesn’t contain any other cannabinoids, terpenes, or plant compounds. The purity might look appealing, but without other plant compounds, it can’t produce the Entourage Effect’s synergistic effect, so we recommend Full Spectrum or Broad Spectrum.

2. Which Type of CBD Extract is Best?

Without a doubt, buy Full Spectrum or Broad Spectrum CBD products. Why? These extracts contain other beneficial compounds like those mentioned above that synergically work together to interact with even more receptors than CBD can, producing an “entourage effect.”

3. What is the Entourage Effect?

Entourage Effect, or Whole Plant Extract, is the term used to describe multiple plant compounds working together synergistically. This synergistic effect increases multiple receptor channels’ activity to enhance the benefits of cannabis or CBD oil.

4. Why are terpenes in CBD important?

Terpenes are compounds found in many plants, including hemp. They are created to provide an aroma for plants and to protect plants from threats such as microorganisms, pathogens, predators, and herbivores, to name a few.

Terpenes go back to 1998 when Professors Raphael Mechoulam and Shimon Ben-Shabat found that the endocannabinoid system demonstrated an “ entourage effect ” when they noticed the activity of receptors had noticeably increased versus an isolated cannabinoid.

Besides that, terpenes have a wide range of benefits such as analgesic and/or anti-inflammatory, mood-enhancing, and modulating CBD effects by producing synergy with cannabinoids.

Here are four terpenes we touched upon above:

  • Beta-Caryophyllene – Beta-caryophyllene is one of the only terpenes that acts as a cannabinoid. It stimulates the nervous system’s CB2 receptors , which modulate inflammation. Unlike CB1 receptors, CB2 receptors do not cause intoxication. However, these neuroreceptors have dozens of potential beneficial effects aside from their observed impact on inflammation.
  • Humulene – Like most terpenes, humulene has been studied for its potential antioxidant and anti-inflammatory effects. Humulene is also one of a few terpenes that have been researched for their potential antimicrobial benefits .
  • Linalool – Along with humulene, linalool has been studied for its potential antimicrobial and antioxidant benefits . This terpene is found in lavender as well as hemp.
  • Bisabolol – A rare terpene, bisabolol, has been studied for its potential ability to reduce skin inflammation , and the antimicrobial potential of this terpene has also been researched.

There are noticeable differences in effects between CBD products with extracts containing terpenes versus CBD products without terpenes. Colorado Botanicals was the only company that showed a terpene profile test from a third-party lab while the other companies didn’t.

5. Why is CO2 extraction better for CBD?

Many hemp extraction processes leave residual solvents behind that can be passed along to the purified extract. CO2, however, is a harmless natural substance, so CO2 extraction doesn’t result in residual solvent contamination.

6. Does CBD Oil Show Up on a Drug Test?

Although the chances are low, yes, CBD oil can show up on a drug test if you use Full Spectrum CBD oil every single day or often. The reason why is because CBD oil can contain up to 0.3% THC.

If you’re worried about THC showing up on a drug test from taking CBD oil, you should purchase Broad Spectrum CBD oils as they are THC-Free. Colorado Botanicals, which earned our #1 spot for the best CBD company of 2022, manufactures Broad Spectrum CBD oil, which we believe is probably one of the best we’ve come across.

7. What part of the hemp plant does CBD come from?

CBD, or generally all cannabinoids, terpenes, and flavonoids, are found in the buds, flowers, and leaves of hemp plants but are usually most concentrated in the flowers.

8. Is hemp seed oil the same thing as CBD oil?

No, hemp oil is not the same as CBD oil and if you’re looking to purchase CBD oil and come across “hemp oil” online, on Amazon, or in a store, then make sure to read the label.

If you read the label and don’t see any acknowledgment of “Cannabidiol” or “CBD,” then it’s not CBD oil.

Although CBD oil is technically hemp oil, it’s mainly used to define hemp seed oil, which is entirely different from CBD oil even though they are from the same plant.

Hemp seed oil is from hemp seeds where they are cold-pressed for oil production, which is used in cooking, beauty products, or a nutritional supplement as it contains nutrients, fatty acids, and protein.

On the other hand, CBD oil is extracted from the flower and buds of hemp, usually using CO2 or Ethanol to pull out the beneficial compounds found in CBD products.

This oil includes CBD, minor traces of other cannabinoids such as CBG and CBN, along with terpenes and flavonoids.

9. Why is MCT oil sometimes used in CBD oil?

  • CBD hemp extract at room temperature crystallizes, which is a natural chemical process, so mixing it with a fatty oil, such as MCT oil, it keeps the hemp extract in liquid form.
  • You might come across other CBD tinctures with hemp seed oil or olive oil as the substitute oil, and it’s for this specific reason.
  • Evenly distributes the CBD hemp extract oil in a tincture by using MCT oil, allowing a consumer to simply fill the dropper to their desired CBD dosage.
  • MCT oil is tasteless.
  • MCT oil is a rich source of fatty acids that has health benefits.

10. Can CBD oil be USDA-certified organic?

Many brands cultivate organic hemp without seeking certification. However, according to leading hemp legal scholars , it is technically possible to achieve USDA-certified organic status for CBD products.

11. Can CBD Oil Expire?

Yes, CBD oil does expire and usually lasts for 12 to 18 months until it goes bad. Purchasing quality CBD products from reputable CBD brands, like the best CBD companies recommended above, is critical to avoiding products that degrade in quality sooner than they should.

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