CBD Oil In Nebulizer

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Nebulizers are a clean, healthy (if somewhat expensive and cumbersome) way to use CBD oil. One advantage is that nebulizers can deliver CBD without combustion. Another advantage is the higher and faster bioavailability of CBD emulsions. IRVINE, CA–(Marketwired – Jul 29, 2016) – Cannabis Science, Inc. (OTC PINK: CBIS), a U.S. company specializing in the development of cannabis-based…

Why People Are Using Nebulizers For CBD Oil

In the unending search for lower impact and less paraphernalia-esque methods of CBD oil administration, a few medical marijuana entrepreneurs have turned over an interesting stone — the pulmonary delivery method known as the nebulizer, previously used exclusively for respiratory illnesses such as asthma, chronic obstructive pulmonary disease (COPD), and cystic fibrosis.

Instead of heating CBD oil to its activation point as with vaping or smoking, a nebulizer sends a mist of aerosolized CBD into the user’s mouth, providing a way to inhale the substance without irritating the throat and lung tissue. The first CBD nebulizers to market are jet nebulizers, which send compressed air through a specially formulated CBD water emulsion, turning it into micro particles that can be inhaled into the lungs.

Can you put CBD oil in a nebulizer though? As cannabis and its extracts are hydrophobic — meaning they don’t like water — this is only possible with some tweaking, which has been the main obstacle in the way of CBD nebulizers until now. And overcoming this roadblock is the main innovation claimed by three innovators now on the scene.

“There’s a whole industry now looking at water solubilization technology,” as Yaron Eshel, the Director of Life Sciences at iCAN:Israel-Cannabis, told The Growth Op. “How do I get this oil and make it into very small molecules so that the body can absorb it? It’s called nanoencapsulation. It’s very standardized in the drug industry, very standardized in the food industry.”

Eshel’s company is one of the first to market cannabis and CBD nebulizers. In collaboration with a technology company called CannRx, they’ve developed two FDA-approved nebulizers, one for medical applications and the other for recreational use. As is the case with another early pioneer — Canna+Neb, whose medically-rated nebulizer starts at $1,999.99 — higher-end CBD nebulizers target conditions which require a consistent flow of CBD, such as insomnia, administered through a mask connected to the device. Recreational-use devices like that produced by fellow trailblazer Pearl2o are less expensive and can be administered via mouthpiece.

The Pros and Cons of CBD Nebulizers

Advocates of CBD nebulizers say they’re healthier than other methods of using CBD, such as smoking or vaping. It’s safe to say that nebulizers are healthier than smoking, but a lot of the evidence against vaping is either tenuous or the product of a poor regulatory environment. If nebulizer emulsions can avoid the contamination and inconsistency that have raised concerns about many low-priced vape pens and CBD vape oils (at the moment, there’s not enough available research to say whether they do or not), then they would have a clear advantage over vaping from a health standpoint as well.

This benefit is magnified for those who seek to use CBD oil for its bronchodilatory effects. Studies have shown that in some cases CBD is as or more effective than common asthma and COPD medications albuterol and ipratropium in opening the airways and increasing airflow to the lungs — the research goes back to 1973, when a study in the New England Journal of Medicine found that “marihuana smoke, unlike cigarette smoke, causes broncho-dilation rather than broncho-constriction.” But while smoked or vaped CBD can cause irritation in the esophagus or lungs for some people, nebulizers can deliver the necessary medicine without causing discomfort of any kind.

In fact, one of the most interesting advantages that nebulizers provide is an ability to deliver CBD without heating or combustion. A Johns Hopkins study found that the metal coils used to heat vape tinctures likely leech significant amounts of heavy metals like nickel and chromium into the vapors that users inhale, an outcome that most would probably prefer to avoid.

Another advantage that is clearly established is the higher and faster bioavailability of CBD emulsions compared with other forms of delivery. This is attributed to both the fact that no CBD is “wasted” upon exhalation, and the strong concentrations of the emulsion itself.

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A subjective plus is the lack of taste and odor in nebulized CBD, and many people appreciate the absence of secondhand smoke or vapor.

There are few drawbacks to CBD nebulizers, but the ones that do exist might be enough to keep them from becoming mainstream. One is the cost, which likely factors into the niche distribution that currently constrains the devices. Even cheap models are hard to find for under $100, while mid-range devices can cost around $500.

To complicate matters, many of these devices only work with special formulations, and a fragmented marketplace of proprietary blends is likely to hinder the widespread adoption of CBD nebulizers. Since CBD is hydrophobic, making one’s own emulsions at home requires a level of chemistry expertise that most people don’t have, which takes the DIY option off the table as well.

Finally, there’s the convenience factor: although some CBD nebulizers are relatively portable, they’re still not exactly svelte, while others are bulkier and hard to use outside of the home. Administering them also requires much more time than taking a CBD capsule or a few puffs of a vape pen.

In a world increasingly focused on price and efficiency, these factors might continue to restrict CBD nebulizers to a dedicated (if highly satisfied) segment of users.

Using CBD oil in a nebulizer for pain relief and breathlessness?

I’m looking into getting my dad to try CBD in a nebulizer as he’s just come out of the hospital with a serious chest infection, they thought he had covid, but all 3 tests came back negative. Can you even put CBD oil in a nebulizer?

He has agreed to give CBD a try as he has Chronic Obstructive Pulmonary Disease (COPD), and I want to see if it will help him. Will CBD help COPD? He has already had the same lung collapse twice in the span of 4 years, and 2 heart attacks in the past year with 4 stents placed in the main heart vessels. He knows he’s dying, and we all know he’s not going to get better; since then I’ve started researching cannabinoids and medicinal cannabis.

As I’ve mentioned: I’m looking for the best recommendations of CBD oil, he is in a lot of pain, constantly breathless. Also, what would the best cannabis oil dosage be for COPD?

We’re not ready to say goodbye yet.
Please help, and thank you.

Osasere Okunloye (Monday, April 19, 2021):

There is no enough research to prove that CBD can cure chronic obstructive pulmonary disease (COPD), although the early signs are encouraging. Early research shows that CBD can help COPD patients breathe more easily by opening up the bronchial passages. Some individuals who have used CBD for COPD have reported positive results.

Before using CBD on COPD, you should be very careful especially since there isn’t enough research on this subject. Advocates of CBD nebulizers say it is the safest method of taking CBD products. There are several advantages of using nebulizers, just as there are also disadvantages. One advantage is that nebulizers can deliver CBD without combustion. Another advantage is the higher and faster bioavailability of CBD emulsions. A disadvantage is that nebulizers can only work with special emulsions since most CBD oils are hydrophobic. If you want to use a nebulizer, you should go for special CBD oils with suitable chemistry that can work with a nebulizer.

Apply extra caution before taking CBD for COPD. See a doctor before taking CBD products along with any other prescribed drugs as CBD products can affect the metabolism of some drugs. Do not stop your medication because of any CBD product as this may be dangerous. Consult your doctor before taking any action to avoid further complications.

Samuel Njoroge (Monday, April 26, 2021):

There are several ways you can consume your daily dosage of CBD oil. One method, putting CBD oil in a nebulizer, has gained popularity in recent years.

Let me take you through some of the pros and cons of nebulizing your CBD oil and recommended CBD oil that you can use. Also, I’ll take you through cautions and warnings you should keep in mind if you decide to nebulize your CBD oil.

CBD oils and nebulizers

Before you nebulize your CBD oil, it’s important you understand that nebulizers diffuse water-soluble preparations. Oils are aquaphobic, meaning they don’t mix with water. For this reason, it’s hard to nebulize your CBD oil.

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Thus if you want to nebulize your CBD oil, you have to use the nanoencapsulation method. In this, CBD emulsion is loaded into a jet nebulizer and is converted to tiny fine droplets like mist.

Advantages of nebulizing your CBD oil

Although vaping and nebulizing may provide a faster method for CBD absorption, the latter doesn’t use heating. This means that intake doesn’t change the chemical composition of CBD except for its physical state.

It provides an easier way to ingest CBD without irritating the throat and lung issues. This is helpful to individuals suffering from lung complications.

You evade the risks of decomposition and deposition of harmful compounds associated with vaping and smoking CBD through nebulizing.

Disadvantages of using CBD oil in a nebulizer

Expensive to purchase a special CBD nebulizer.

The cost of CBD emulsion is higher than that of CBD oil per dose.

If you can afford to purchase the CBD nebulizer and emulsion, you can now realize the full health benefits of a diffused CBD in managing COPD and asthma.

Cannabis Science Develops Inhalation Medication for Those Suffering Asthma/COPD via Nebulizer, Targets National Markets

July 29, 2016 14:22 ET | Source: Cannabis Science, Inc. Cannabis Science, Inc.

Encino, California, UNITED STATES

IRVINE, CA–(Marketwired – Jul 29, 2016) – Cannabis Science, Inc. ( OTC PINK : CBIS ), a U.S. company specializing in the development of cannabis-based medicines, is pleased to announce they will release an inhalation medication for those suffering asthma/COPD for use in patient nebulizers. This product will be offered in states where marijuana is legal on a national basis.

Based on State by State laws the Company can proceed with studies in the 25+ states approved for medical marijuana, and lay the groundwork for expanding into other states across the nation as legislation changes and more states become legal. This could also be seen as a mechanism to verify the effectiveness of CBD/THC on patients that use the medication as a bronchodilator.

Studies have shown CBD/THC to be effective as a bronchial dilator and in many cases being better that Albuterol or Ipratropium.

Studies have demonstrated that THC may act as a temporary (1-2 hours) bronchodilator, especially when ingested. The New England Journal of Medicine, published a 1973 study that stated, “Marihuana smoke, unlike cigarette smoke, causes broncho-dilation rather than broncho-constriction [narrowing of the air passages] and, unlike opiates, does not cause central respiratory depression [i.e. a decrease in breathing].”

Another long-term study (20 years) done from 1985 to 2006, examined 5,000 subjects from three American cities. The researchers questioned the participants about their cannabis and cigarette use, and tested lung capacity as well as rate of air flow out of their lungs. To their surprise, the researchers found that at low to moderate levels of cannabis smoking, lung volume and air flow rates both increased with each “joint year” (365 joints), up until seven joint-years (or 2,555 joints).

Bronchodilatory effects – Studies performed in the 1970’s at the University of California Los Angeles by Donald Tashkin have shown that both inhaled and orally ingested THC produce bronchodilation for up to two hours after administration [1] . Further investigations by the Respiratory Pharmacology Laboratory in Paris have shown that CB1 receptor activation inhibits cholinergic contraction in a concentration-dependent fashion, offering a possible mechanism for acute bronchodilation associated with cannabis intake [2] . Although smoked cannabis also has this effect, any kind of combustion creates other lung irritants that would be counterproductive for COPD treatment.

Chronic obstructive pulmonary disease (COPD) is a progressive lung disease that makes it difficult to breathe. “Progressive” means that the disease gets worse over time.

Approximately 12 million people in the United States have been diagnosed with COPD. Many more may be affected and not know they have it.

CHRONIC OBSTRUCTIVE PUMONARY DISEASE (COPD) LUNG FUNCTION & CANNABIS STUDIES COMPLETED

Marijuana has long been reported to relieve symptoms of asthma. Now, research explains why marijuana’s main ingredient may help patients breathe easier.

How Cannabinoids may help COPD

  • Cannabinoids relieve inflammation
  • Cannabinoids are anti-microbial
  • Cannabinoids support / modulate the immune system and its response to infection and disease
  • Cannabinoids are expectorants
  • Cannabinoids are analgesic (pain relief)
  • Cannabinoid medicine has little to no side effects
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In COPD, air flow is restrictive due to:

  • The airways + air sacs have a lack of elasticity
  • Air sac destruction and inflammation
  • Increased mucus and clogged airways

Published last week in the British Journal of Pharmacology, a new study shows marijuana may have a similar effect on the airways as some asthma medications.

Using samples of human lung tissue, French researchers found that THC could block muscle contractions caused by a signaling molecule called acetylcholine.

Acetylcholine is responsible for maintaining muscle tone of the airways and also contributes to contractions in asthma attacks. Interestingly, asthma medications block the same molecule, but from a slightly different angle.

“They prevent the acetylcholine from binding to its receptor,” explains Dr. Donald Tashkin, who was not involved with the study. “But THC works proximal to that. It doesn’t have any competitive effect for binding to receptors. It just prevents the acetylcholine from being released.”

Dr. Donald Tashkin, a lung expert and professor of medicine at UCLA, was part of the team that first discovered marijuana’s effect as a bronchodilator. In 1973, his group published a study in the New England Journal of Medicine that found airways widen in both healthy and asthmatic individuals after smoking marijuana.

“It also succeeded in reversing experimentally induced asthma, in a manner that was comparable to what could be achieved with a standard therapeutic bronchodilator that was widely used at the time.”

Dr. Tashkin explains, “I don’t know if anyone’s ever studied the effect of vaporized THC on airway smooth muscle, but my guess is that it would lead to bronchodilation.”

About Cannabis Science, Inc.

Cannabis Science, Inc., takes advantage of a unique understanding of biologic processes to provide novel treatment approaches for common ailments and for those disorders where current treatments are relatively unsuccessful and understanding remain incomplete. Cannabinoids have an extensive history dating back thousands of years, and currently, there are a growing number of peer-reviewed scientific publications that document the increasingly complex underlying biochemical pathways that cannabinoids modulate. The Company works with leading experts in drug development, medicinal characterization, and clinical research to develop, produce, and commercialize novel therapeutic approaches for the treatment for illnesses caused by infections as well as for age-related illness. Our initial focus is on skin cancers, HIV/AIDS, and neurological conditions. The Company is proceeding with the research and development of its proprietary drugs as a part of this initial focus: CS-S/BCC-1, CS-TATI-1, and CS-NEURO-1, respectively.

This Press Release includes forward-looking statements within the meaning of Section 27A of the Securities Act of 1933 and Section 21E of the Securities Act of 1934. A statement containing words such as “anticipate,” “seek,” intend,” “believe,” “estimate,” “expect,” “project,” “plan,” or similar phrases may be deemed “forward-looking statements” within the meaning of the Private Securities Litigation Reform Act of 1995. Some or all of the events or results anticipated by these forward-looking statements may not occur. Factors that could cause or contribute to such differences include the future U.S. and global economies, the impact of competition, and the Company’s reliance on existing regulations regarding the use and development of cannabis-based drugs. Cannabis Science, Inc., does not undertake any duty nor does it intend to update the results of these forward-looking statements. Safe Harbor Statement. The Private Securities Litigation Reform Act of 1995 provides a ‘safe harbor’ for forward looking statements. Certain of the statements contained herein, which are not historical facts are forward looking statements with respect to events, the occurrence of which involved risks and uncertainties. These forward-looking statements may be impacted, either positively or negatively, by various factors. Information concerning potential factors that could affect the company are detailed from time to time in the company’s reports filed with the Securities and Exchange Commission.

Cannabis Science, Inc.
Dr. Allen Herman
Chief Medical Officer (CMO)
[email protected]
Tel: 1-888-263-0832

Cannabis Science, Inc.
Investor Relations
Teresa Misenheimer
[email protected]
Tel: 1-888-263-0832

Cannabis Science, Inc.
Mr. Raymond C. Dabney
Director, President & CEO, Co-Founder
[email protected]
Tel: 1-888-263-0832

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