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Shu Suddenly, the holy light fell from the sky and fell on Elder Zhaixingzi s body sh n , reshaping the Taoist body.
Good fortune. Although everyone admired in their hearts, deep down in their hearts, they were still very uneasy.
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Zhai Xingzi and the Ancient Phoenix Empress were both experienced veterans, can you inject cbd oil and they were also thinking about this issue.
She seems to be stalling for time, what is she trying to do Delusional general, what are you trying to do Delaying time is not good for you.
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Buffing Ye Fan raised his eyebrows, raised his head and raised his chest.
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glanced at the audience, and said, If it wasn t for Ye Fan, the ancient Phoenix Dynasty can you inject cbd oil would have Cbd Products can you inject cbd oil been reduced to ruins, and the entire star had become a colony of the demon race.
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Nishang Ye Fan turned and walked towards Princess Nishang s sickbed, facing the former beauty.
In this case, it is impossible for him to let Emperor Wu give up can you inject cbd oil the Dawu Dynasty and accompany him back to Tianshu Xing.
Young Master Ye actually has such strength, it s can you inject cbd oil not lost to any emperor Even if the Empress is at her peak, I m afraid she can t do it Ye Fan is a monster, ah no, a god , he is saving us all At this moment, everyone could no longer express can you inject cbd oil their admiration and admiration for Ye Fan, watching his sword move, it was like seeing the sword saint coming.
Look, it s the ghost eyed demon who will start the Skyscraper again, now it s troublesome.
Xingzhe Hand Xingxingzi mobilized all body sh n internal energy and gathered it fat 19 gummy worm can you inject cbd oil on the palm of his hand.
Can You Inject CBD Oil
Can you “inject marijuanas,” as the satirical memes suggest? Yes, but it’s a really, really stupid thing to do, according to a new study.
A new study found that injecting pure THC triggered schizophrenia-like behaviors in subjects. But, uh, does anyone actually consume weed this way?
The study, conducted by schizophrenia researchers at the Veterans Affairs Healthcare System in Connecticut, and recently published in Neuropsychopharmacology, involved shooting up 22 healthy individuals with 2.5mg THC, 5mg THC, or a placebo (0mg THC). The subjects had previously been “exposed” to cannabis, but none had been diagnosed with cannabis use disorder.
After three separate days of mainlining pure THC, the subjects reported experiencing schizophrenia-like symptoms, increased anxiety, altered perceptions, euphoria, and a host of memory and speech issues. Their blood also showed increased levels of cortisol, the primary stress hormone. Not surprisingly, the researchers concluded that THC produces psychotic behaviors, and more studies are needed to see how cannabinoid receptors may contribute to psychotic disorders.
Usually when we see anything about injecting THC or “marijuanas,” it comes from satirical social media accounts that claim shooting up weed can cause everything from suddenly turning someone gay to spontaneous death (again, these are memes). But intravenous administration of THC is a standard (though not terribly common) practice in cannabis studies, since it gives researchers precise control over dosing. The only problem with this study and others like it is that no one actually injects pure THC. There’s a reason why most consumers prefer to smoke or vape cannabis, after all.
When someone smokes, let’s say, a one-gram joint rolled with weed containing 25 percent THC, that joint contains, roughly, 250mg of THCA, the form of THC that doesn’t get anyone high. Heat converts some THCA into THC — the stuff that gets people lit — but only some THCA turns into the psychoactive form. The average time that heat is applied to the joint isn’t long enough to convert all of the THCA to THC. Furthermore, a bunch of converted THC gets lost in the smoke that wafts from the joint, and even more THC gets stuck in the ash.
So, by the end of it, even if just one person smoked that entire 1-gram joint to the face, they’re only getting a small fraction of that potential 250mg THC, not to mention a cornucopia of other compounds such as other cannabinoids, terpenes, flavonoids, and polyphenols — which all may interact with our brain’s cannabinoid receptors, dulling the negative effects of THC.
In other words, shooting someone up with 2.5mg or 5mg pure THC is kind of a lot, especially for non-stoners, which this study focused on.
In addition to there being next-to-no people who shoot up THC distillate or diamonds on a regular basis, no one shoots up actual weed, either. Back in the ‘70s and ‘80s, some idiots tried that, and they developed what’s called “intravenously injected marijuana disorder.” Basically, folks would boil weed buds into a “broth,” pull that filtered broth up into a syringe, then inject it. Rather than getting lit, they got sick AF instead, which included bouts of vomiting, intense muscle pains, and serious heart problems.
Here’s the thing about IV marijuana disorder, too: There are practically no new case studies on it after 1986, suggesting that only a handful of people did it back in the day. Why? Obviously, it sucks, and it’s potentially life-threatening. Which is why, today and in the past, folks have stuck to puffing their pot.
Does this mean that everything about the VA study is bogus? Not entirely. We know that the endocannabinoid system plays a role in some mental disorders, and cannabis use can aggravate some psychotic symptoms in people particularly prone to them. However, many cannabis patients consume weed to alleviate symptoms of their personality or mood disorders, too, so the issue isn’t black-and-white, nor is it clear-cut.
Oh, and in case if you’re wondering if you can snort weed, yeah, technically, that’s possible. But you’ll end up blowing pot-snot all day and never catching a buzz.
Cannabis in the arm: what can we learn from intravenous cannabinoid studies?
Cannabis is widely used recreationally and for symptomatic relief in a number of ailments. However, cannabis has been implicated as a risk factor for the development of psychotic illness. For forty years researchers have utilised intravenous preparations of Δ(9)-THC, as well as several other phytocannabinoids, in a laboratory setting. The intravenous route has the most reliable pharmacokinetics, reducing inter-individual variation in bioavailability and is well suited for the delivery of synthetic compounds containing a sole pharmacological moiety. Given the association between cannabinoids and psychotic illness, there has been a resurgence of interest in experimental studies of cannabinoids in humans, and the intravenous route has been employed. Here in a critical review, we appraise the major findings from recent intravenous cannabinoid studies in humans and trace the historical roots of this work back to the 1970’s.
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Singh K, Jamshidi N, Zomer R, Piva TJ, Mantri N. Singh K, et al. Int J Mol Sci. 2020 Aug 29;21(17):6265. doi: 10.3390/ijms21176265. Int J Mol Sci. 2020. PMID: 32872551 Free PMC article. Review.
Ganesh S, Cortes-Briones J, Ranganathan M, Radhakrishnan R, Skosnik PD, D’Souza DC. Ganesh S, et al. Int J Neuropsychopharmacol. 2020 Dec 3;23(9):559-570. doi: 10.1093/ijnp/pyaa031. Int J Neuropsychopharmacol. 2020. PMID: 32385508 Free PMC article.
Panlilio LV, Justinova Z. Panlilio LV, et al. Neuropsychopharmacology. 2018 Jan;43(1):116-141. doi: 10.1038/npp.2017.193. Epub 2017 Aug 28. Neuropsychopharmacology. 2018. PMID: 28845848 Free PMC article. Review.
Andre CM, Hausman JF, Guerriero G. Andre CM, et al. Front Plant Sci. 2016 Feb 4;7:19. doi: 10.3389/fpls.2016.00019. eCollection 2016. Front Plant Sci. 2016. PMID: 26870049 Free PMC article. Review.