Taking CBD oil and melatonin together is largely considered safe, and may be more effective at beating insomnia than taking the supplements on their own CBD for sleep gummies with melatonin can ease insomnia symptoms and help you fall asleep faster. Learn more about if this natural remedy is right for you. Thinking of taking CBD oil with Melatonin and need to understand the effects, dosage, and safety? Here's the guide you need – from the Prescription experts!
Melatonin and CBD Oil: Can It Help You Sleep Better?
When looking for better sleep, people will try just about anything. For years, science has supported the use of melatonin in cases of insomnia and other sleep disorders. But recently, CBD oil has been gaining traction as a potential solution to a range of problems, including sleep disturbances.
When combined, do CBD oil and melatonin help you sleep better? Are there side effects of using CBD oil and melatonin together? Moreover, how can you use CBD oil and melatonin safely?
In order to get the most from any supplement routine, it is important to understand the answers to these questions. Here’s what you need to know about CBD oil, melatonin, and getting a good night’s sleep!
CBD Oil and Melatonin Interaction
Melatonin and CBD oil both promote sleep, but work in different ways to do so. Unlike regular vitamins and supplements, when you take melatonin it is treated by the body as if it were created internally. Instead of breaking it down and converting it into something usable, your body is able to metabolize melatonin immediately, without further processing. The same is true for CBD oil.
CBD replicates your body’s own endocannabinoids in order to exert its therapeutic effects. Melatonin supplements work in a similar way, replicating endogenous melatonin to regulate your circadian rhythm, or natural sleep-wake cycle.
During normal waking hours, there is very little melatonin circulating in your body. Instead, there are other hormones like cortisol at work, which keep you alert and awake. As day turns to night and natural sunlight levels drop, the levels of melatonin in your system start to rise as the sun goes down, peaking overnight and slowly reducing toward the morning. Taking a melatonin supplement before bed increases the amount of melatonin in the body and can encourage rest and deeper sleep.
CBD oil promotes sleep by reducing cortisol levels and anxiety . Cortisol levels should naturally fall overnight, but if you’re overly stressed, they can spike and remain high, making falling asleep near impossible. CBD oil has been shown to inhibit the release of cortisol , and could help reduce the stress that’s barring you from a good night’s sleep. Since CBD oil can also help with anxiety, your overall stress levels should dip and remain lower, making relaxation and a good night’s sleep more achievable.
With all this in mind, taking CBD oil and melatonin together may create a powerful aid to fight insomnia. Because cannabidiol and melatonin act on different systems in the body, currently, the two substances can act synergistically to enhance the quality of your sleep. Melatonin signals your body that it is time to sleep, while CBD oil works in tandem to provide overall relaxation and calm. Together, they deliver a one-two punch to insomnia and sleep disturbances.
Side Effects of Using CBD oil and Melatonin
Neither CBD oil or melatonin have many recognised side effects. CBD oil is widely considered to be safe with little to no side effects . The World Health Organization published its own report on the use of CBD oil and found, “ … CBD does not produce the effects that are typically seen with cannabinoids such as THC… it is generally well tolerated, with a good safety profile.” Melatonin has few reported side effects , but some users may experience headaches, depression, or irritability. Combining CBD oil and melatonin may mitigate some of these side effects.
Long-term use of melatonin is discouraged, as its efficacy decreases with chronic use. Courses of melatonin should be limited to three months or less. CBD can be used more chronically. If you decide to use the two supplements together, you may find that using both melatonin and CBD initially helps to establish good sleep patterns. Once these sleep patterns have been established, you could decrease your regimen to include CBD only.
Limited use of melatonin can help regulate your sleep-wake cycle, similar to hitting the refresh button on your natural circadian rhythm, times when your sleep cycle may be disrupted e.g. after international travel across time zones Regular use of CBD oil can regulate the body’s cortisol production, so you’ll feel less stressed day and night, which is great for your sleep hygiene and overall well being.
Melatonin and CBD are both metabolised via the cytochrome p-450 pathway, so any side effects of melatonin may theoretically be exacerbated by adding CBD. Perhaps you should include a warning about this and just a recommendation to start with a low dose of CBD if you are adding it to an existing melatonin supplement.
How to Safely Use CBD Oil and Melatonin Together
When combining CBD oil and melatonin it’s important to take dosage into account. As melatonin is often purchased in standardized doses it is easiest to maintain this amount and add CBD oil into your routine gradually. Start with a low dose of CBD oil and slowly increase your dosage over time if necessary—you don’t want to overload the body with too many sleep-inducing compounds at once. Allow your body and mind time to adjust to the effects of CBD oil.
Take note of whether taking CBD oil throughout the day or just at night is more beneficial for promoting sleep. You might consider keeping a sleep journal for the first month of using CBD oil and melatonin together to gauge which dosage and at what time(s) of day are most effective when it comes to using CBD for sleep.
Alternatively, you can purchase CBD products that already have melatonin included. This removes the need to delicately balance your quantities. If using these products, start with the dosage suggested in the information pamphlet and gradually increase until you experience the desired effect.
Melatonin is best used when you can get a full 8 hours of sleep. To avoid feeling groggy in the mornings, take your melatonin or CBD oil/melatonin combination product when you have enough time to devote to sleep. As with anything that can promote or induce sleep, be careful driving, operating heavy equipment or doing anything that requires extreme concentration until you know how the combination will impact you.
As a precaution, speak to your doctor before combining the two supplements. You can also speak with a cannabis doctor who can give you personalized recommendations on dosages and specific CBD products to help with sleep.
Best CBD Oil to Use with Melatonin
If you’re ready to try a product that contains CBD oil and melatonin, or want to purchase CBD oil to add into your existing melatonin routine, there are two main factors to consider: delivery method and quality.
For a melatonin-CBD hybrid product, the most common delivery formats are combination gummies , capsules, tinctures , and drops . Simply take the recommended dose prior to going to bed. Because capsules or gummies travel via the digestive system, they take longer to take effect. For this reason, take your melatonin-CBD combo gummies or capsule about an hour before bed to ensure you’ll feel the effects right on time.
If you don’t know when you’ll be going to bed, or want a little more flexibility, sublingual CBD-melatonin drops or tinctures may be best for you. These CBD products are absorbed directly into the bloodstream through the skin under the tongue and go to work in as little as a half hour. The only difference may be that you don’t feel the effects as strong or for as long as you would a gummy or capsule.
If you are already taking melatonin and want to add CBD oil, try starting with drops or a tincture. This format will allow you complete control over your CBD dose, ensuring you can gradually increase or decrease the amount as needed.
Before taking melatonin, CBD oil, or a combination of the two, consult with your physician. By having this conversation, you can determine if these are safe options for you and work out a potential starting dose. Both CBD oil and melatonin can interact with some commonly prescribed medications .
If you don’t see effects immediately, don’t lose sleep over it! Be patient and take your time adding CBD oil to your daily or nightly routine.
Can I Mix CBD Oil With Melatonin
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CBD Sleep Gummies with Melatonin
Many people do not get as much sleep as they would like to get. Nearly one in three adults show at least one of the symptoms or signs of insomnia.  Even when able to get to sleep, the actual sleep itself may be shallow and fitful. Pharmaceutical answers like powerful sleeping drugs aren’t everyone’s first choice. A quick review of modern sleeping medications shows that many of these drugs are habit-forming.  This has led many people to look for natural sleeping remedies, including CBD sleep products and products with melatonin. CBD, or cannabidiol, is a natural product of the cannabis plant, but unlike the more famous THC, it does not produce a psychoactive “high.” Melatonin is the body’s natural sleepiness hormone, and can be taken orally to help with sleep. CBD sleep gummies with melatonin combine two natural medicines that can help with sleep.
Sleepiness signals in the body
A normally functioning human body regulates energy levels throughout the day with a variety of systems. Our hormones help with this. Hormones are naturally produced chemical signals that travel throughout the body and cause effects beyond where they are synthesized. Melatonin is the sleepiness hormone. Melatonin production is suppressed by daylight, specifically the blue part of the spectrum.
For most of the time humans have been around, the presence of blue light was synonymous with daytime. With the exception of fleeting phenomena like lightning or bioluminescent organisms, as soon as the sun began to set, blue light dropped until it almost reached zero. It is no wonder that our bodies use a system that relies on blue light to regulate sleep! Only after the invention of electric lighting did we start to spend periods of time when there was blue light after sunset.
One of the negative consequences of artificial illumination is that our age-old sleepiness control systems can be thrown out of whack. This is one reason why sleep experts advise people who are having trouble sleeping to avoid electronic screens at night. The blue light in your smartphone’s screen could be preventing melatonin from accumulating enough for you to grow tired. 
Melatonin and CBD for sleep
Melatonin can be taken orally in order to send the sleepiness signal to the body and brain. Melatonin supplementation has been found to reduce sleep latency, or the time it takes to fall asleep. Taking melatonin can also increase total sleep time as well. 
The story with cannabidiol and sleep is a little more complicated. CBD can help with issues that are common impediments to healthy sleep. Anxiety can be reduced by taking CBD, and anxiety is a common insomnia risk factor. CBD can also help with restless leg syndrome, which involves an unbearable urge to move one’s legs. Restless legs cause people to have difficulty sleeping, and cannabidiol has been found to be an effective restless leg syndrome treatment.
Combining melatonin and cannabidiol has the potential to offer a number of benefits. This is why CBD sleep gummies with melatonin have become a popular choice for how to fall asleep fast.
Can I take melatonin with CBD sleep gummies?
Yes. The body produces melatonin naturally, so any time you consume cannabidiol, you are combining melatonin with CBD. In fact, some people find CBD sleep gummies with melatonin are the best way to fall asleep.
Do melatonin gummies actually work?
The short answer is yes. Many studies have found that melatonin supplementation decreases the time it takes to get to sleep, increases the amount of time spent asleep, and improves the overall quality of sleep.  The longer answer is that, while melatonin is a proven method to help you sleep, the dosage matters. Doses of melatonin as low as half a milligram have been found to be nearly as effective as doses in the 50-milligram range in terms of shortening sleep latency, or the time it takes to fall asleep. However, higher doses seem to be more effective at maintaining sleep through the night. 
How long do CBD sleep gummies take to start working?
Cannabidiol takes anywhere from one to six hours to reach peak concentrations in the bloodstream when taken orally.  This means that taking CBD sleep gummies right before getting into bed might not have too much of an effect in terms of triggering sleepiness. However, taking CBD sleep gummies before bed could help with maintaining sleep, which may provide help for restless legs. Melatonin reaches its highest concentration in the bloodstream an hour after being taken orally  , so CBD sleep gummies with melatonin should be taken around an hour before bed.
How many CBD gummies should I take for sleep?
The number of CBD gummies you should take to help you sleep depends on a number of factors. First, the amount of CBD in the gummies may change from brand to brand. Also, if the CBD sleep gummies are CBD sleep gummies with melatonin, take note of how much melatonin is present. Personal experiences will vary, but if you pay attention to those two numbers you should be able to determine what works best for you. Start with a small amount, and if they are sugar-free gummies that contain sorbitol, large amounts of gummies may cause intestinal upset. 
Taking CBD Oil With Melatonin, Dosage, Effects, and Safety
Have you ever just laid in bed and stared at the ceiling for what seems like hours trying to go to sleep? You may be looking for supplements and methods for trying to get better sleep, making you question if you can take CBD oil with melatonin.
In this article, we’ll answer your questions regarding the use of CBD oil and melatonin, the dose, the potential effects, and compatibility. First, let’s start with a quick summary.
Can I take CBD oil with melatonin? CBD oil and melatonin are considered safe to take together. They have sleep benefits that complement each other, especially for insomnia. Take a 1-mg melatonin tablet, split it into two and take half each night. Combine with 10mg of CBD oil or take 0.25/0.50 mg for every one pound weight as a guide.
Keep this quick answer in mind as we get into more of the specifics and other considerations to take into account.
To begin with, the following is a brief explanation of available research and information.
It’s important to clarify that both CBD oil and melatonin together can interact with other medications you may be taking. So, before following any of the proceeding information, we suggest you look to obtain your doctor’s consent.
The doses of either CBD oil or melatonin can vary if you’re taking them together for a night of better sleep.
In general, the dosage will depend on an array of factors such as age, weight, severity of insomnia, and other health conditions you may be experiencing. More on dosage shortly.
There is still no solid validity or reliability that taking CBD oil and melatonin together helps better sleep. So, only your doctor or relevant health professional can guide you on what’s good for you and your condition.
How CBD oil and melatonin work
In order to understand more about how these elements work together, let’s recap on both components.
Melatonin, in simple terms, is a hormone made by the pineal gland. It helps your body know when it’s time to sleep and wake up.
In other words, this hormone plays a crucial role in regulating your sleep-wake-up cycle, also known as the circadian rhythm.
Normally, your body makes more melatonin at night. The production of this hormone starts after sunset and reduces in the morning. Being exposed to harsh light in the late evening or at night can block melatonin production.
The production of melatonin in the body is commonly affected by factors such as age and exposure to artificial light.
This is especially relevant to current generations as they are regularly exposed to artificial light through phones, tablets, and computers. Therefore, melatonin production is treating affected.
The result of having insufficient melatonin production is insomnia or other sleep-related problems.
This is why many people will use melatonin supplements to treat their sleep problems.
These supplements work by activating the melatonin receptors in the brain, known as MT1 and MT2 receptors.
These receptors are the ones that inform or send signals to your brain that it’s time to sleep. Also, melatonin helps with the following as well:
- Alleviating jet lag
- Treating insomnia efficiency and quality
- Minimizing the times you wake up during your sleep
- Reducing sleep latency
- Balancing the sleep cycles for people who go through complete or partial blindness
CBD oil, also known as cannabidiol, is a non-psychoactive extract of the cannabis plant. It’s a supplement that’s recently becoming more popular.
CBD oil is commonly used to help with anxiety, stress, mood swings, immunity, appetite, digestion, metabolism, inflammatory responses, insomnia, other sleeping disorders, and different chronic pains.
CBD oil works by interacting with the endocannabinoid system (ECS) through cannabinoid receptors found all over the body.
There are two types of endocannabinoid receptors; CB-1 and CB-2:
- CB-1 receptors are more active in the central nervous system
- CB-2 receptors are more active in the immune system
The ECS regulates many vital bodily functions, which help in maintaining balance within the body.
It’s through these receptors and interactions that CBD oil appears to be able to affect many of the body’s functions, including your sleep-wake cycles.
Connections between CBD oil and melatonin taken together
There is indeed a connection between CBD oil and melatonin.
Firstly, it’s that both have a strong positive impact on your sleep-wake cycle, especially helping with insomnia.
Secondly, the MT1 and MT2 melatonin receptors and CB-1 and CB-2 CBD receptors that influence sleep fall into the same group called G-protein coupled receptors.
This means they have a similar structure, process, and mechanism in which they influence the process of the sleep-wake cycle.
It’s this connection between CBD oil and melatonin that makes their benefits on sleep complement one other.
Is taking CBD oil with Melatonin safe?
Further research is necessary to validate this statement, but in general, both are safe to take together.
Both elements present naturally beneficial effects on sleep, so taking them together can be more effective, especially for insomnia.
But as we always advise, consult your doctor before making any changes.
To support this further, melatonin reverses hormonal disruption triggered by external factors supporting faster sleep.
On the other hand, CBD oil can help alleviate anxiety and stress symptoms, supporting a night of quality sleep.
As such, both CBD oil and melatonin combined can offer you a more sustained level of quality sleep, with minimal waking patterns.
The right dose for taking CBD oil with melatonin
Although taking both together is generally considered safe, make sure you don’t overload sleeping substances.
This can make your day inactive and drowsy. Your dose should help you with a quality sleep at night to make sure you are alert, active, productive, and happy during the day.
When it comes to finding the right dose for taking CDB oil with melatonin, start with the lowest dose possible. And as directed by your doctor, gradually increase your dose until you feel the balanced effects.
With that being said, below, we’ve added a short guide for each CBD oil and melatonin dose that can help you with safe dosing.
Melatonin is often sold in standard doses of 1-milligram tablets. So you can use this standard dose and split it into two nights.
Cut the tablet into two and take one half each night. Even a small dose of 0.3 to 0.5 milligrams is still effective, depending on your condition.
Some may require doses such as 5 mg, but they may come with some side effects such as headaches, nausea, weird dreams, and wooziness.
Now taking high doses of melatonin, especially anything higher than 5mg, is seen to be ineffective. So, taking a dose higher than 5mg will be unnecessary and is not worth the side effects.
CBD Oil dosage
The effects of CBD oil for sleep or insomnia are heavily dependent on the dose.
When taken in small amounts, it may act as a stimulant. However, taking large doses can induce sedation.
This is why figuring out the right dose is important with CBD oil.
The good news is that CBD has not been reported to have any adverse or fatal side effects. So, while you’re free to experiment, it’s advisory to keep it moderate as it can and does show mild side effects.
10 mg of CBD oil is a good starting point. Low doses of CBD oil can provide stimulating effects. As a general rule, consider 0.25 mg for every one pound of body weight. So, for an average 200-pound adult, 50 mg would be a guideline dose.
If you need a stronger dose, then consider 0.5 mg for every one pound of body weight. So again, for a 200-pound adult, that would be a dose of 100 mg to experience stronger effects.
We hope this has provided you with an overview of whether to take CBD oil with melatonin. As always, consult your doctor before making any potentially significant changes to your medications.